WATER/AQUA/EAU, ISONONYL ISONONANOATE, PROPANEDIOL, DIMETHICONE, PENTYLENE GLYCOL, SALIX ALBA (WILLOW) BARK EXTRACT, GLYCERIN, DIMETHYL ISOSORBIDE, SODIUM CITRATE, SODIUM POLYACRYLATE, BUTYLENE GLYCOL, CAPRYLYL GLYCOL, PHENOXYETHANOL, KAOLIN, POLYSILICONE-11, BIOFLAVONOIDS, GLYCOPROTEINS, HYDROLYZED OATS, XANTHAN GUM, ALLANTOIN, CHLORPHENESIN, LACTIC ACID, FRUCTOOLIGOSACCHARIDES, WITHANIA SOMNIFERA ROOT EXTRACT, ISOHEXADECANE, FRAGRANCE/PARFUM, PANTHENOL, HELIANTHUS ANNUUS (SUNFLOWER) SEED EXTRACT, LAMINARIA DIGITATA EXTRACT, ISOCETETH-20, YEAST EXTRACT, DIPOTASSIUM GLYCYRRHIZATE, SALVIA HISPANICA SEED EXTRACT, LACTOBACILLUS FERMENT, PRUNUS MUME FRUIT EXTRACT, 1,2-HEXANEDIOL, AMMONIUM POLYACRYLOYLDIMETHYL TAURATE, OLEA EUROPAEA (OLIVE) FRUIT OIL, LYSINE, MANNOSE, SODIUM MANNOSE PHOSPHATE, OCIMUM SANCTUM LEAF EXTRACT, HYDROLYZED SODIUM HYALURONATE, SODIUM HYALURONATE, TOCOPHERYL ACETATE, POLYSORBATE 80, POLYSORBATE 20, GLYCERYL ACRYLATE/ACRYLIC ACID COPOLYMER, CARRAGEENAN, POTASSIUM SORBATE, SODIUM BENZOATE, COPPER SULFATE, PROLINE, CYAMOPSIS TETRAGONOLOBA (GUAR) GUM, LECITHIN, PVM/MA COPOLYMER, PHYTIC ACID, BRASSICA OLERACEA CAPITATA (CABBAGE) LEAF EXTRACT, SALVIA HISPANICA SEED OIL, SEA SALT, CERAMIDE NP, BETA-SITOSTEROL, OENOTHERA BIENNIS (EVENING PRIMROSE) OIL, PERILLA OCYMOIDES SEED OIL, TOCOPHEROL, GLYCINE SOJA (SOYBEAN) OIL, BHT, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, HEXYL CINNAMAL, LIMONENE, LINALOOL, GERANIOL

1. After cleansing and toning, dispense three pumps onto fingertips and apply to the face and neck, avoiding the eye area.
2. Use morning and evening.
3. Follow with moisturizer.
4. Discontinue use if persistent irritation occurs.

10 powerful benefits in every bottle

1. Instantly hydrates and locks in moisture all day.
2. Exfoliates to promote natural cell renewal.
3. Soothes and calms misbehaving skin.
4. Minimizes the appearance of pores in just one week.
5. Delays and diminishes the appearance of fine lines.
6. Strengthens skin’s moisture barrier.
7. Maintains skin resilience and elasticity.
8. Boosts radiance and luminosity.
9. Evens skin tone.
10. Defies signs of sallowness and yellowness.

Combining the best of science & nature

Our experts bring together plant extracts and advanced skin science to provide simple solutions for your unique needs.

Amino Acids

Help minimize the appearance of pores and improve the look of skin’s elasticity.

Olive Extract

Naturally derived from upcycled olives to provide powerful antioxidant protection against environmental aggressors, boost radiance and diminish the appearance of fine lines.

White Willow Bark & Lactic Acid

Naturally occurring power duo exfoliates to help promote natural cell renewal.

Nutrilite White Chia Peptide

Soothes skin and provides antioxidant protection against environmental aggressors and irritation.

Nutrilite White Chia Liposome

Improves skin’s moisture barrier and locks in moisture.

Defy the appearance of aging

The Artistry Skin Nutrition Defying Serum easily fits into your morning and evening routine. Follow these steps to keep your skin looking its healthy best.

Step 1: Cleanse

Remove makeup if needed, then use your favorite Artistry Skin Nutrition or Artistry Studio™ cleanser.

Step 2: Tone

Help stabilize and nurture skin with your Artistry Skin Nutrition or Artistry Studio toner.

Step 3: Treat

Apply the Defying Serum. For even greater benefits, start with the Artistry Skin Nutrition Vitamin C + HA3 Daily Serum, followed by the Defying Serum.

Step 4: Moisturize

In the morning, add your daily moisturizer and eye cream. In the evening, use your nighttime moisturizer and eye cream.

Step 5: Extra Support

As the final step in your routine, layer on the Artistry Skin Nutrition Multi-Defense UV Protect sunscreen with SPF 50+ (AM) or the Artistry Skin Nutrition Sleeping Mask (PM).

Get to know the Defying Serum

Watch Artistry Skin Care Expert and Licensed Esthetician, Michelle D'Allaird Brenner explain the key differences between the Defying and Correcting Serums, how you can maximize your routine by using these two serums with key products and where they fit within your routine.

Play Video

The Ideal Skin Care Routine

Play Video

Which Serum Is Right for Me?

Play Video

Better Together

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5.05.0 out of 5 stars. Read reviews for Artistry Skin Nutrition™ Defying Serum.4 ReviewsThis action will navigate to reviews.4 out of 4 (100.00%) reviewers recommend this product

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Effectiveness4.8Effectiveness, 4.8 out of 5Value5.0Value, 5.0 out of 5

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PamG

• IBO review

Charlotte, NCReview1Votes5IBO reviewYes5 out of 5 stars.

Defying Serum

a month agoConsistency has been the key for me with this product. Remembering to put it on right after my toner in the AM and PM (then moisturizer a minute later) has resulted in a very smooth and even skin tone, and a very youthful look overall. I don’t ever remember my skin looking this healthy..

• Yes,
• I recommend this product.

Helpful?(5)(0)ReportEffectiveness5.0Effectiveness, 5.0 out of 5Value5.0Value, 5.0 out of 5

Tay7787

• IBO review

Pefferlaw, OnReview1Votes5IBO reviewYes5 out of 5 stars.

Amazing product!

a month agoI've been using this serum for 2 weeks and it has already drastically lightened the scarring on my face!

• Yes,
• I recommend this product.

Helpful?(5)(0)ReportEffectiveness5.0Effectiveness, 5.0 out of 5Value5.0Value, 5.0 out of 5

loompa

• IBO review

Vancouver, BCReview1Votes4IBO reviewYes5 out of 5 stars.

This is a great product

a month agoIt is a hydrating product. I use the virtual beauty app to track my changes for 5 days and my skin age remains at 27. I m turning 40 next year

• Yes,
• I recommend this product.

Helpful?(4)(0)ReportEffectiveness4.0Effectiveness, 4.0 out of 5Value5.0Value, 5.0 out of 5

Sabrina R

• IBO review

Clermont, FLReview1Votes3IBO reviewYes5 out of 5 stars.

New Skincare!

27 days agoI am LOVING this product so far. This lightweight serum is an amazing addition & makes my skincare routine feel even more luxurious.

• Yes,
• I recommend this product.

Helpful?(3)(0)ReportEffectiveness5.0Effectiveness, 5.0 out of 5Value5.0Value, 5.0 out of 5

1 Review in Another Language

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1. Are any of the ingredients or technologies in the Defying Serum exclusive?

Yes. The white chia liposome and white chia protein peptide, part of the Nutrilite™ white chia blend, both originate from white chia seed grown on our own Nutrilite farm in El Petacal, Mexico, as well as a NutriCert™ -certified partner farm in Bolivia. These ingredients and their associated skincare technologies are exclusive to Amway.

2. What testing or laboratory support was conducted?

Clinical, consumer, and safety testing has been performed to support safety and efficacy claims to ensure that the products are well tolerated and efficacious and satisfy consumer expectations.

3. What is the shelf life of the Defying Serum, and how long can I use it after it has been opened?

The shelf life of the unopened product is three years (36 months). Once the product is opened, we recommend that it be used within 12 months to ensure full product efficacy.

4. How should the Defying Serum be stored?

All Artistry Skin Nutrition skin care products should be stored in a cool, dry place, out of direct light.

5. Why does the serum bottle vary in color?

The Defying Serum features a unique vignette design that blends the signature colors of the Artistry Skin Nutrition solution set it is formulated to pair best with, in a semi-transparent bottle. This means that as the serum inside is used up, the coloring seen on the outside of the bottle will change. The Defying Serum features the lighter blue/green colors of the Balancing and Hydrating lines.

6. Is the Defying Serum packaging recyclable?

Artistry Skin Nutrition Defying Serum cartons are recyclable* and produced from paper that has been sourced from responsibly managed forests by a supplier that practices sustainable forestry.

*Where appropriate recycling facilities are available; check locally.

7. Is the Defying Serum compatible with other Artistry skincare products?

Yes, the serum was created to be aesthetically compatible with other Artistry Skin Nutrition and Artistry products.

8. Can I use the Defying Serum and the Correcting Serum together?

It is safe to use both, by either combining or alternating as part of your (AM + PM) routine. For best results, we recommend selecting a serum that’s formulated to address your unique skin concerns; however, some consumers may prefer a lighter serum in the morning and a richer serum at night.

9. Can the Defying Serum be used around the eyes?

When applying the Defying Serum, avoid the delicate eye area. As with any skin care product, avoid getting Artistry Skin Nutrition formulas directly into the eyes.

10. If I experience any skin sensation after applying the Defying Serum, what should I do?

The Defying Serum has been fully tested for safety. However, every individual’s skin is different. If you experience a skin reaction, stop using the product. Consult your doctor if a rash occurs. Do not use on damaged or broken skin.

11. Can the Defying Serum be used during pregnancy?

Safety studies of cosmetics are not conducted on pregnant women. Because skin condition changes in pregnancy, whether to use or not use this product should be discussed by the woman and her physician.